To delete a registry key with a .reg file, put a hyphen (-) in front of the RegistryPath in the .reg file. For example, to delete the Test subkey from the following registry key:
[-HKEY_LOCAL_MACHINE\Software\Test]
To delete a registry value with a .reg file, put a hyphen (-) after the equals sign following the DataItemName in the .reg file. For example, to delete the TestValue registry value from the following registry key:
HKEY_LOCAL_MACHINE\Software\Test
“TestValue”=-